The Difference in the Entourage Effects for Each CBD Consumption Method

*This article is purely informational and does not constitute medical advice. Consult your healthcare provider about CBD.

The Entourage Effect
The Entourage Effect

The Entourage Effect

The entourage effect and how it translates differently for each CBD consumption method is a virgin topic, intriguing yet necessary for a better decision-making purchasing process for CBD patrons.

For today’s topic, we are going to attempt to understand how the entourage effect differs for each consumption method. 

What is CBD?

CBD is cannabidiol is the second-most abundant cannabinoid found in cannabis. One among the hundreds of cannabinoids, CBD, unlike its sibling compound THC (delta-9-tetrahydrocannabinol), does not cause “high” or intoxication. 

To date, there hasn’t been any serious public health issue concerning CBD per se. The World Health Organization says, “In humans, CBD exhibits no effects indicative of any abuse or dependence potential…”


The studies presented do not imply that CBD can treat the condition mentioned. Moreover, the information presented here is not meant as a substitute or alternative to information from healthcare professionals. Consult your healthcare provider about CBD before use.

What is the Entourage Effect?

The entourage effect is the suggested positive effect derived from the combination of cannabinoids, terpenes, and other cannabis compounds. This theory is better explained by this phrase “the entirety of the effect is greater than the sum effects of its contributing parts.”

The entourage effect theory suggests that the addition of other cannabis compounds to the CBD extract enhances the cannabinoid activity of CBD.

What are the Perceived Differences of the Entourage Effect for Each CBD Consumption Method?:

Studies comparing the entourage effect experience for each consumption method are yet to begin. But as veteran users know by now, cannabis’s effect wildly varies from one method to the next. 

Before anything else, it’s important to understand that cannabis’s effect in itself is complex, coupled with the uniqueness of each individual’s physiology and biochemistry. So, much of what we’re relaying shouldn’t be assumed as something “absolute.”

By looking at what we know about cannabinoids and the absorption method of each consumption type, we can logically get an inkling of what the entourage effect is like for each CBD consumption type. 

RELATED: The CBD Entourage Effect: How it Enhances CBD’s Effects


CBD edibles are discreet ways of taking CBD, plus, they come in delectable flavors resembling candies or gummies. One downside of taking CBD edibles is that you may need to wait for a few hours before the effects kick in. 

CBD capsules are CBD extract encapsulated in a medical-grade capsule. They’re great for people who love non-fuss pre-measured CBD dosages. 

Through ingestion, cannabinoids go through the liver where it further gets metabolized. For example, THC gets converted into 11-hydroxy-THC, a metabolite that is 5 times more active than THC. 

Logically, if we put it this way, the entourage effect may be slightly more intense with ingestion. However, this hasn’t been proven yet, since no clinical study, in existence, discusses this topic thoroughly. 


CBD tinctures and oils are some of the most popular forms of CBD products in the market today. Taken sublingually, you put a couple of drops under your tongue, hold it there for at least 30 seconds, before swallowing. 

Through the sublingual method, the product gets absorbed in the blood directly through the tissue at the back of your tongue. 

There are conflicting results with the sublingual method regarding the entourage effect. In a 2020 study by Raup-Konsavage W.M. et. al, they found no evidence of the “entourage effect.”

Ironically, the study’s results show that CBD in isolate form (pure) performed better in the experiment. 

On the other hand, anecdotal evidence and CBD brands swear customers get the entourage effect from CBD products formulated in “full-spectrum.” These products are CBD-based but with an addition of cannabis’s other active cannabinoids (including THC in limited amounts), terpenoids, and more. 


Topical application is done by applying CBD-based creams, lotions, ointment, and the like on the skin.

Unfortunately, there isn’t enough anecdotal evidence supporting that the entourage effect happens when CBD extract is applied to the skin. 

CBD, in topical application, isn’t as potent or as holistic compared to other methods of consumption like ingestion. 


Inhalation is the quickest way to experience CBD’s effect/s. Upon inhaling CBD, from your lungs, it goes straight to your bloodstream. 

CBD inhalation is done in two ways; smoking or vaping. 

Although inhalation skips the liver, throwing cannabinoids altogether directly to your bloodstream, CBD smoked in flower form is still one of the most “full-spectrum” of all cannabinoid sources. 

Usually achieved through smoking, CBD extracts in vape liquid form are still pretty refined compared to cannabis flowers. 


Smoking CBD involves an oil rig that looks like a water pipe. Flowers with high-CBD content can simply be rolled and smoked. However, take note, that in this way, you’re consuming THC as well. 


Often through a vaporizer pen, vaping is a nice alternative to smoke if you want the same CBD concentration but without the strong, raw experience one often has when smoking. 

The Wrap

The comparison of the entourage effect experience between each type of CBD consumption method might get murky before it gets clearer. 

The entourage effect, in itself, is still a theory. 

As more studies do the leg work on analyzing the chemistry of cannabis, we hope to get a better picture of this topic. 

“These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

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