*This article is purely informational and does not constitute medical advice. Consult your healthcare provider about CBD and drug interactions.



CBN vs CBG; what is the difference between CBG and CBN?

By now, many of you will have heard of cannabis and its benefits. More so with Cannabidiol or CBD, which has taken the United States by storm. Recent statistics show 64% of Americans are familiar with CBD, and 33% of American adults have used it once or more.

But one of the great discoveries scientists have found in cannabis is the power of the different cannabinoids found within it. 

While, yes, Tetrahydrocannabinol or THC and CBD take center stage most of the time, Cannabinol and Cannabigerol are slowly becoming famous for beneficially healthy reasons.

What is the difference between CBG and CBN?


Cannabigerol or CBG is often dubbed the “mother” of all cannabinoids. That is because of its chemical nature, where every cannabinoid found in the Cannabis plant can be made by naturally processing CBG. 

Safe to say, without CBG, it is challenging to create CBD, THC, and all the other cannabinoids in nature’s way.

Like CBD, CBG is non-psychoactive and present in different varieties of hemp commonly used in the US. What that means is that you don’t get intoxicated or high compared to THC.

Again, similar to all other cannabinoids, CBG interacts with the endocannabinoid system of the human body; however, it has a key advantage versus CBD by interacting with the system directly.

RELATED: The Endocannabinoid System: Why is it special?


On the other hand, Cannabinol or CBN is considered one of the rarer cannabinoids and makes up about only 1% of all cannabinoids found in the cannabis plant. 

Compared to the other cannabinoids, it is formed from the degradation of Tetrahydocannabinolic Acid or THCA, the precursor to THC. Because of how it is created, CBN is more commonly found in older cannabis plants.

Despite CBN’s rare presence in cannabis, it is surprisingly the first cannabinoid ever discovered some time near the end of the 19th century. Its chemical structure was elucidated in the 1930s, artificially created in the lab by 1940 – the same time as CBD and two years before THC.

What is CBN good for?

Studies on CBN are quite limited compared to other cannabinoids; however, the results of these studies tell a promising and beneficial story to CBN’s use.

CBN for sleep

Does CBG help you sleep? CBN is more popularly known to elicit a good night’s sleep. 

In one of the earlier studies of CBN, it was found to have good sedative effects, with the participants reporting drowsiness. However, the study used it in conjunction with THC. It is believed that CBN enhances the effects of THC.

But, in a more recent study, CBN was discovered to have sedative effects similar to Diazepam, a drug used to treat panic disorders, anxiety, alcohol withdrawals, and seizures. The study elaborates that 2.5 – 5mg of CBN is equivalent to 5 – 10mg of Diazepam or half the amount of CBN for the same sedative effect.

CBN for Anti-inflammatory effects

One study from 2009 takes a look at cannabinoids for use as novel anti-inflammatory drugs. While CBD and THC, again, took center stage, CBN made an appearance as well. 

The researchers stated that CBN looks to be a promising treatment for inflammatory conditions such as allergic asthma.

CBN for pain relief

For pain, which is better CBN or CBD?

A study in 2019 looked to answer that question and compare it to CBD. The researchers found that CBN at 1mg/ml had the same effect of pain relief as CBD at 5mg/ml. But, more interestingly, the researchers discovered that CBN and CBD created a longer-lasting effect when combining them at a 1:1 ratio.

What is CBG good for?

Like CBN, research on CBG isn’t as extensive compared to CBD and THC. However, CBG is no slouch either and has promising results, especially for pain, inflammation, and appetite.

CBG for appetite stimulation

Often, THC is the cannabinoid sought after for increasing appetite. But CBG has been proven by two separate studies to increase appetite. 

In one study, UK researchers found that a dose of 120 – 240 mg/kg increased the food intake by double the amount. And at the dose of 240 mg/kg, the latency, or the time between meals, was significantly reduced.

In the other study, the researchers reinforced that a dose of 120 mg/kg increased food intake and was substantial in negating the effects on food intake caused by chemotherapy.

RELATED: CBD Dosage Guide for Beginners and Veterans

CBG for pain relief and inflammation

In another comparison to THC, studies believe that CBG has the ability to relieve pain and inflammation and can be used as novel drug candidates for treating such ailments. In another study, the researcher even claims that CBG is an even more potent pain reliever than THC.

RELATED: What the Research Says on CBD and Inflammation

Can you take CBG and CBN together?

Yes, CBN and CBG are not currently known to have any contradicting effects. Instead, many products are combining the two to create effects that enhance and balance each out.

Dubbed the “Entourage Effect,” scientists theorize a form of cannabinoid synergy that occurs when using a cannabinoid in the presence of other cannabinoids. 

Similar to a previously mentioned study, the presence of CBN with THC enhances each other’s effects. Likewise, the presence of CBG and CBN together, more so with THC and CBD, is theorized to create an effect greater than the sum of its parts.

The Wrap: CBG vs CBN, which is better?

Is CBG better than CBD, vice versa?

To cut a long story short, the answer is: it depends. One or the other isn’t better per se, nor is either worse than the other. Instead, the performance of the two cannabinoids will matter on what they will be used for.

If anything, the data and evidence presented above paint a picture that CBN and CBG work well together. More so, both CBN and CBG have been found by studies to be supportive of other cannabinoids such as CBD and THC.

A key takeaway from this article in comparison between the two; studies suggest that CBN is excellent for sleep while CBG is great for appetite stimulation.

But at the end of the day, always remember to consult with a health professional before using CBG, CBN, CBD, or THC. While these cannabinoids have been shown to have beneficial effects, it is also good practice to see if these effects will help you as well.

“These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.”

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